HomeProcedures発毛メソセラピー(頭皮注入)

発毛メソセラピー(頭皮注入): Downtime

Very mild Category: 薄毛治療・植毛 Last updated: 2026-07-13
Hair growth mesotherapy (scalp injection therapy) delivers agents said to support hair growth and a healthier scalp environment — such as growth factor preparations, minoxidil, and blends of vitamins and amino acids — directly into thinning areas of the scalp using fine needles or a dedicated delivery device. Because no scalpel is involved, downtime is generally considered relatively mild, and even when needle marks or redness appear, they are said to settle within a few hours to a few days for most people. On the other hand, many of the agents used include medications and preparations that have not been approved in Japan, and how results appear — and how noticeable they are — varies from person to person. A typical plan is said to involve multiple sessions every 2–4 weeks, combined with oral and topical AGA (androgenetic alopecia) treatment. This page covers what to expect from the day of treatment onward, along with everyday precautions. For your actual course of recovery and whether this treatment is right for you, always see a physician for an examination and consultation.
Important notice about unapproved medications

Some of the products described on this page have not been approved as pharmaceuticals in Japan. They are imported personally under the responsibility of the treating physician, and they are not guaranteed to have the same efficacy and safety as domestically approved medications. In some cases, no approved medication with the same active ingredient exists in Japan. If a health problem occurs, it will not be covered by Japan's Relief System for Sufferers from Adverse Drug Reactions. Safety information from other countries differs from product to product. Before undergoing treatment, be sure to receive a thorough explanation from your doctor.

DowntimeA few hours to 2…
PainMild
MakeupFrom the next da…
Work / social lifeOften possible f…

Downtime at a glance

Needle marks and redness typically last a few hours to a few days. They are easy to hide under the hair, and returning to work or going out is often said to be possible from the same day or the next day.

Typical downtime is A few hours to 2–3 days (if bruising occurs, it often fades within about 1–2 weeks), and most people feel comfortable being seen in public after Often possible from the same day to the next day (scalp redness and needle marks are easily hidden by the hair). How much swelling or bruising appears varies from person to person, depending on constitution and the extent of treatment.

Recovery timeline: treatment day to final result

Day of treatment

Needle marks, redness, and stinging may appear at the injection sites. You will generally be advised not to wash your hair on the day of treatment, and showering is usually allowed as long as it stays from the neck down. It is safer to avoid alcohol, strenuous exercise, saunas, and other activities that strongly boost circulation. A hat can often be worn from the same day if it is clean, but follow your clinic's instructions.

The next day

For many people, redness and stinging start to fade at this stage. Hair washing can generally be resumed gently with lukewarm water (the timing varies by clinic). Work and outings are usually possible as normal, and the needle marks are said to be hidden by the hair and barely noticeable.

Day 3

Redness and stinging have mostly settled for many people by this point. Mild itching can occur as part of the healing process — cool the area rather than scratching and watch how it goes. Exercise and saunas can generally be resumed gradually from around this time.

1 week later

The needle marks are barely noticeable for most people. Any bruising also starts to fade around this time. Hair coloring and perms irritate the scalp, so it is safer to wait a little longer — about 1–2 weeks after treatment — until the redness has completely settled.

2–4 weeks later (typical timing for the next session)

The scalp has usually returned to normal by this stage. Hair growth mesotherapy is generally done as a series of sessions every 2–4 weeks, and it is said to be too early to judge visible change at this point. Your doctor will adjust the timing of the next session based on the condition of your scalp.

3–6 months later (evaluating results)

After multiple sessions combined with ongoing oral and topical treatment, this is said to be the stage at which changes in hair shedding and the growth of fine new hairs are evaluated, often by comparing photographs. Because results vary greatly from person to person, whether to continue is decided together with your doctor based on your progress.

Bars show approximate swelling levels (individual results vary).

Common symptoms

SymptomLikelihoodWhen it appearsHow long it lastsNotes
Needle marks and pinpoint rednessHighImmediately after treatmentA few hours to 2–3 daysRedness may appear along the injection points, but it is often hidden by the hair and said to be hard to notice.
Slight oozing of bloodMediumImmediately after treatmentSame day onlyBecause the scalp has a rich blood supply, a small amount of blood may ooze from the needle marks, but it is generally said to stop quickly with light pressure.
Pain and stingingMediumImmediately after treatment to the next dayA few hours to 2–3 daysA prickly sensation when the area is touched may linger, but in most cases it is said to settle within a few days.
Swelling and a feeling of scalp tightnessMediumImmediately after treatment to the next dayA few hours to 2 daysIn areas that received a larger injection volume, the scalp may temporarily feel tight. With injections near the hairline, swelling can occasionally drift down toward the forehead.
ItchingLowThe next day to a few days laterA few daysMild itching can occur as part of the healing process. Scratching can prolong the redness, so manage it by cooling the area, and consult a medical institution if it is severe.
BruisingLowSame day to the next day1–2 weeksBruises are usually hidden by the hair, but if one appears in a visible spot such as the hairline, it can be covered with bangs or makeup.

When can I do what? (Daily-life restrictions)

ActivityTypically OK fromKey point
Hair washingFrom the next day (gently, without rubbing)You will generally be advised to skip washing on the day of treatment to avoid irritating the needle marks or introducing infection. Once you resume, it is safer to wash with the pads of your fingers rather than your nails, using lukewarm water. Some clinics allow washing from the evening of the treatment day.
ShowerFrom the same day (from the neck down, avoiding the scalp)When you may wet your scalp varies by clinic, so follow the instructions of the medical institution where you were treated.
Bathing (soaking in the tub)From the next dayA long soak on the day of treatment boosts circulation and can intensify redness and itching, so it is safer to avoid it.
Makeup and face washingAs usual from the same dayBecause the treatment area is the scalp, facial makeup and face washing are generally said not to be restricted. If you had injections near the hairline, avoid rubbing that area.
AlcoholFrom the next dayDrinking on the day of treatment may make redness and bruising more likely, so it is safer to avoid it.
ExerciseLight exercise from the next day; strenuous exercise from around 2–3 days laterHeavy sweat reaching the needle marks can cause irritation and itching.
Sauna and hot-stone bathsFrom around 2–3 days laterHeat and humidity boost circulation and can prolong redness, so it is safer to hold off for a few days.
Hair coloring and permsFrom around 1–2 weeks laterThe chemicals irritate the scalp, so it is safer to wait until the redness has completely settled. Confirm the timing with the medical institution where you were treated.
Hats and wigsOften said to be fine from the same dayChoose something clean, and it is safer to avoid prolonged tightness or trapped humidity.
Scalp massage and topical hair-growth productsFrom around a few days to 1 week later (follow your doctor's instructions on when to resume topical products)Avoid strong stimulation to the scalp until the needle marks have settled. If you are using a topical product, checking with your doctor in advance about when to pause and resume it will make things go smoothly.
Can you hide it? Concealment difficulty ●○○○○ / Because the treatment area is the scalp, redness and needle marks are said to be naturally hidden by the hair in most cases. If you had injections along your part line or hairline, you can cover the area with a hairstyle change, such as switching your parting or wearing your bangs down. A hat can also often be worn from the same day (choose a clean one and avoid anything too tight), so this is considered a treatment that is unlikely to be noticed even if you have plans to see people. A mask is unnecessary for concealment, since it has nothing to do with the treatment area. How well it can be hidden varies from person to person.

Pain and anesthesia

The typical pain level is Mild. Topical numbing cream or cooling may be used alongside the treatment. If you are worried about pain, consult your doctor in advance — including about which delivery method to use. The scalp is a sensitive area, so injections there are said to cause a noticeable pricking pain. Many clinics use cooling, vibration, ultra-fine needles, or topical numbing cream to reduce discomfort, and where a needle-free delivery device can be chosen (such as systems that use electrical currents to help the agents penetrate), pain is said to tend to be milder. How it feels varies from person to person.

Tips for a smoother recovery

Risks and side effects (the honest version)

If a symptom lingers or gets worse, do not try to judge it yourself — contact the medical institution where you had the procedure.

Spacing and combining with other procedures

If you have an important event such as a wedding or a photo shoot, allow for the possibility of redness or bruising and finish the treatment at least 1 week before the date. If injections along the hairline or part line are planned, build in extra leeway. A typical plan is said to involve multiple sessions at a pace of once every 2–4 weeks. Each session is performed after the scalp's redness and overall condition have settled, so your doctor will adjust the interval and number of sessions based on your progress.

Combined procedureTimingWait timeReason
AGA Treatment (Oral and Topical Medication)Same day OKCombination is generally assumedMesotherapy is generally said to be performed in combination with baseline oral and topical treatment. The foundation is medications approved in Japan (such as oral finasteride and topical minoxidil) — noting that oral minoxidil is not approved in Japan — and the combination is decided under a doctor's diagnosis.
Hair Transplant SurgeryWait requiredRoughly 1 month before and after transplant surgery (your surgeon's instructions take priority)It is common to avoid needle stimulation to the scalp immediately before and after transplant surgery. So as not to interfere with the period in which the transplanted hairs take root, follow your surgeon's judgment on when to pause and resume mesotherapy.
Scalp Microneedling (Dermapen-Type Devices)Wait requiredRoughly 1–2 weeksBoth treatments apply fine stimulation to the scalp, so having them too close together can intensify redness and stinging. Your doctor will adjust the order and interval.
Facial Injectables (Botox, Hyaluronic Acid Filler, etc.)Same day OKMay be possible on the same dayBecause the treatment areas differ — scalp versus face — these can often be done on the same day. Adjustments may be made depending on your condition and any anesthesia used, so if you would like both, mentioning it when you book will make things go smoothly.

Who it may suit / who should be cautious

May suit you

  • Those who have started to notice more shedding or a loss of hair volume
  • Those who want to consider a direct approach to the scalp in addition to oral and topical AGA treatment
  • Those who are still hesitant about surgery such as a hair transplant and want to start with scalpel-free options
  • Those who want to address hair thinning while keeping downtime short
  • Those who want to start by improving their scalp environment

Consider carefully

  • Those who are pregnant or breastfeeding
  • Those with alopecia areata, a scalp skin condition, or a scalp infection (treating the underlying cause takes priority)
  • Those with a history of allergy to the agents being injected
  • Those who are not comfortable with the explained risks of using medications unapproved in Japan
  • Those with medical conditions or medications that lead their doctor to judge the treatment unsuitable

Frequently asked questions

Does hair mesotherapy hurt?
The scalp is a sensitive area, so injections there are often said to cause a pricking pain. Many clinics ease it with cooling, vibration, or topical numbing cream, and where a needle-free delivery device can be chosen, pain is said to tend to be milder. Because sensitivity varies from person to person, if you are worried, consult your doctor in advance — including about which delivery method to use.
Can I go to work the next day? Will people notice?
Needle marks and redness are almost always hidden by the hair, and returning to work as usual from the same day or the next day is often said to be possible. If you had injections along your hairline or part line, you can cover the area by changing your parting or wearing your bangs down. A hat can also often be worn from the same day. Recovery varies from person to person.
When can I wash or color my hair?
The usual guidance is to skip washing on the day of treatment and resume gently with lukewarm water from the next day (some clinics allow washing from the same evening). Hair coloring and perms irritate the scalp, so it is safer to wait until the redness has settled, around 1–2 weeks later. Always follow the instructions of the medical institution where you were treated.
How many sessions will I need?
A common plan is said to be around 5–10 sessions at intervals of 2–4 weeks, continuing while monitoring your scalp's condition. This is not a treatment that produces visible change in a single session; changes in shedding and the growth of fine new hairs are typically evaluated over about 3–6 months. The number of sessions and time frame needed depend on the state of your hair thinning, so discuss them with your doctor.
Are the injected agents government approved?
Many of the agents used in hair mesotherapy — growth factor preparations, exosomes, injectable minoxidil formulations, and others — are medications and preparations that have not been approved in Japan. They are used under the judgment and responsibility of the physician, but because they have not undergone the same review as approved medications, it is important to receive an explanation before treatment covering their unapproved status, how they were obtained, whether an approved medication exists in Japan, and their side-effect information — and to make your decision only once you are fully satisfied.
How is this different from treatment with oral or topical medication alone?
The foundation of AGA treatment is generally considered to be oral medications approved in Japan (such as finasteride) and topical medications (such as topical minoxidil). Mesotherapy is often used alongside them as a supplementary option that delivers agents directly to the scalp, while the evidence for its effectiveness on its own has been noted to be limited. Also be aware that oral minoxidil is not approved in Japan. Discuss how to structure your treatment with your doctor based on a diagnosis.
Can women have this treatment?
It is sometimes performed for female hair thinning (such as diffuse thinning). However, the medications and concentrations that can be used may differ from those for men, and it is generally not performed during pregnancy or breastfeeding. Because female hair thinning has a wide range of possible causes — including anemia and thyroid conditions — we recommend first seeing a physician to identify the cause.
Will my hair go back to how it was if I stop?
AGA (androgenetic alopecia) is considered progressive, and hair is thought to gradually return to its original course once treatment stops. With mesotherapy as well, maintaining results is generally assumed to require ongoing sessions and combination with oral and topical treatment. It is reassuring to start only after discussing a long-term plan — including cost and time frame — with your doctor.
This article was written and is kept up to date by our editorial team, based on general knowledge in cosmetic surgery and aesthetic dermatology, the package inserts of the products and medical devices involved, and publicly available information from government agencies and medical societies. It is not an advertisement for any specific medical institution. Editorial policy
This article is for general informational purposes only and is not an advertisement for any specific medical institution. All figures are typical guidelines; results and recovery vary from person to person. Please see a physician before making any final decision. The information on this site is provided for general informational purposes only and is not a substitute for diagnosis, treatment, or medical advice. Final decisions about a procedure's suitability, risks, combinations, and intervals must always be made after being examined by a physician.